Introduction.
Rewind™ represents a paradigm shift in how we approach menopausal health—not by managing symptoms, but by addressing the underlying physiological cascades that create them. As women transition through perimenopause and into menopause, they face a complex interplay of hormonal, microbiological, and circulatory changes that profoundly impact their quality of life. While conventional medicine often treats these changes as isolated symptoms requiring separate interventions, emerging research demonstrates that these changes are interconnected and require a comprehensive, systems-based approach.
The formulation of Rewind™ is grounded in this understanding. Rather than offering temporary symptom relief, it provides targeted nutritional support to help restore two fundamental pillars of feminine wellness: the vaginal microbiome ecosystem (Foundation Pillar) and hormonal-metabolic balance (Vitality Pillar). This white paper examines the scientific rationale behind each component of the Rewind™ system and the clinical evidence supporting its use.
Understanding the Menopausal Cascade.
The Estrogen Decline and Its Consequences.
The menopausal transition is characterized by a progressive decline in ovarian estrogen production, beginning in perimenopause and continuing through postmenopause. This hormonal shift triggers a cascade of physiological changes that affect multiple body systems simultaneously.
Impact on Vaginal Health:
- Thinning of vaginal epithelium (vaginal atrophy)
- Decreased natural lubrication
- Altered vaginal pH from protective acidic (3.8-4.5) to more alkaline environment
- Disruption of protective Lactobacillus-dominant microbiome
- Increased susceptibility to infections (bacterial vaginosis, yeast infections, urinary tract infections)
Impact on Systemic Health:
- Elevated cortisol levels and dysregulated stress response
- Decreased blood flow to genital tissues
- Reduced sexual arousal and diminished orgasmic response
- Mood disturbances and energy depletion
- Sleep disruption and decreased vitality
These changes do not occur in isolation—they compound one another, creating what we term the "menopausal cascade effect."
Pillar 1: The Restoration System.
Flora Restoration Complex (20 Billion CFU, 13-Strain Probiotic System).
The Critical Role of Vaginal Microbiome in Women's Health.
The vaginal microbiome represents one of the most specialized microbial ecosystems in the human body. In healthy reproductive-age women, this ecosystem is dominated by Lactobacillus species, which produce lactic acid and hydrogen peroxide to maintain an acidic pH that protects against pathogenic organisms.
During and after menopause, estrogen decline disrupts this delicate balance. The vaginal epithelium becomes thinner, glycogen stores (which feed protective Lactobacilli) decrease, and pH shifts toward neutral or alkaline levels. This creates an environment where pathogenic bacteria and fungi can flourish, leading to recurrent infections, odor, discomfort, and painful intercourse.
The Science of Vaginal-Specific Probiotics.
Recent clinical research has demonstrated that oral administration of specific Lactobacillus strains can colonize the vaginal tract and restore protective microbial balance. A landmark 2003 study published in FEMS Immunology and Medical Microbiology found that oral administration of Lactobacillus rhamnosus GR-1 and Lactobacillus fermentum RC-14 for 60 days resulted in restoration of normal vaginal flora in 37% of women with asymptomatic bacterial vaginosis, compared to only 13% in the placebo group.¹
Subsequent research has confirmed these findings across multiple studies. A 2021 systematic review in Frontiers in Cellular and Infection Microbiology concluded that specific Lactobacillus strains demonstrate broad-spectrum antagonistic activity against vaginal pathogens, superior adhesion to vaginal epithelial cells, and anti-inflammatory properties that support tissue healing.²
The Rewind™ Probiotic System: Targeted Strain Selection.
The Flora Restoration Complex contains 20 billion colony-forming units (CFU) of 13 clinically-studied strains, specifically selected for their ability to colonize vaginal tissue, restore natural moisture, and eliminate dryness through multiple interconnected mechanisms.
Understanding the Moisture-Microbiome Connection.
Before menopause, the vaginal ecosystem creates its own natural lubrication through a sophisticated biological process. Estrogen promotes the maturation and proliferation of vaginal epithelial cells, causing them to accumulate glycogen. This glycogen-rich environment becomes the foundation for vaginal health—when epithelial cells naturally shed, they release glycogen into the vaginal lumen. Beneficial Lactobacillus strains metabolize this glycogen through fermentation, producing lactic acid that creates the characteristic acidic pH (3.8-4.5) of a healthy vagina.
This acidic environment does three critical things: it maintains optimal conditions for protective bacteria, creates an inhospitable environment for pathogens, and stimulates the continuous production of cervicovaginal fluid (CVF)—the body's natural lubrication that keeps the vaginal mucosa moist, supple, and comfortable.
When estrogen declines during menopause, this cascade breaks down. The vaginal epithelium becomes thin and atrophic, glycogen production decreases dramatically, Lactobacillus populations plummet, pH shifts from acidic to alkaline, and the continuous lubrication system fails. The result: dryness, thinning tissue, painful intercourse, and vulnerability to infection.
The solution isn't adding external moisture—it's restoring the system that creates moisture naturally.
That's precisely what the Rewind™ probiotic complex does. By reintroducing the specific Lactobacillus and Bifidobacterium strains that colonize vaginal tissue, the formula helps restart the natural moisture-production cycle. As these beneficial bacteria re-establish themselves, they begin producing lactic acid again, lowering pH, stimulating epithelial cell health, and allowing the body to resume its natural lubrication processes.
The 13-Strain Synergistic System
Each strain in the Rewind™ formula was selected for specific, complementary functions that work together to restore the complete vaginal ecosystem:
The Foundation Colonizers: Establishing Territory.
L. acidophilus (Lactobacillus acidophilus)
L. acidophilus produces both lactic acid and hydrogen peroxide, creating the dual protective environment necessary for vaginal health. As one of the most extensively studied vaginal probiotics, this strain has demonstrated effectiveness in managing bacterial vaginosis, yeast infections, and symptoms associated with vaginal atrophy including dryness. When administered orally, L. acidophilus successfully colonizes the vaginal tract within 7-14 days, beginning the process of pH restoration that allows natural moisture to return. Research shows L. acidophilus plays a protective role against adverse pregnancy outcomes and bacterial vaginosis, highlighting its fundamental importance in vaginal health.
L. rhamnosus (Lactobacillus rhamnosus)
This strain exhibits exceptional adhesion properties to vaginal epithelial cells and creates a protective biofilm barrier that serves as the foundation for a healthy microbiome. L. rhamnosus generates hydrogen peroxide, organic acids, and lactic acid, showing broad-spectrum antagonistic action against urinary tract pathogens including E. coli, Candida albicans, and Gardnerella vaginalis. Its ability to firmly adhere to vaginal tissue makes it particularly effective at preventing pathogen colonization—essentially claiming territory before harmful bacteria can establish themselves. Oral administration of L. rhamnosus significantly increases its abundance in the vagina starting at day 7, with peak colonization occurring by week 2-3.
L. plantarum (Lactobacillus plantarum)
L. plantarum is a potent lactic acid producer with strong antimicrobial activity against pathogenic organisms including E. coli. Beyond pathogen defense, this strain contributes to the metabolic ecosystem by efficiently fermenting available glycogen, adding to the lactic acid pool that maintains protective pH levels. Its robust nature makes it one of the most resilient Lactobacillus species, able to survive gastric acid passage and effectively colonize the lower genital tract.
The Immune Modulators: Reducing Inflammation, Promoting Healing
B. lactis (Bifidobacterium lactis)
This Bifidobacterium strain employs competitive exclusion to crowd out pathogenic bacteria, essentially occupying ecological niches that would otherwise be available to harmful organisms. When administered orally, B. lactis significantly increases beneficial bacteria abundance in the vagina starting at day 7. Beyond competition, B. lactis supports the overall microbial diversity necessary for a resilient vaginal ecosystem—one that can resist disruption from antibiotics, sexual activity, or hormonal fluctuations.
B. bifidum (Bifidobacterium bifidum)
B. bifidum plays a specialized role in supporting localized immune function within vaginal tissue. By modulating the immune response, it helps reduce the chronic low-grade inflammation that often accompanies vaginal atrophy and dysbiosis. This anti-inflammatory action is crucial for tissue healing—inflamed tissue cannot properly produce glycogen, secrete protective mucus, or maintain barrier integrity. By calming inflammation, B. bifidum creates the conditions necessary for tissue restoration.
B. longum (Bifidobacterium longum)
B. longum specifically reduces inflammation and promotes tissue healing in the vaginal epithelium. This healing support is particularly important for postmenopausal women whose vaginal tissue has become thin, fragile, and prone to micro-tears during intercourse. As tissue heals and thickens under B. longum's influence, it regains the capacity to produce glycogen and support robust Lactobacillus populations—completing the restoration cycle.
The pH Restoration Team: Recreating the Acidic Environment.
L. fermentum (Lactobacillus fermentum)
L. fermentum is recognized as one of the most clinically validated strains for vaginal health restoration. Its primary function is robust lactic acid production, which rapidly lowers vaginal pH from the alkaline levels (>5.0) common in menopause back toward the protective acidic range (3.8-4.5). Lower pH is strongly correlated with higher Lactobacillus colonization and protection against pathogenic overgrowth. By quickly establishing an acidic environment, L. fermentum creates favorable conditions for other beneficial strains to thrive while simultaneously making the environment hostile to pathogens.
L. reuteri (Lactobacillus reuteri)
L. reuteri contributes to pH balance through steady lactic acid production, but its benefits extend beyond acid production. This strain has demonstrated ability to colonize both the gut and vaginal tract when taken orally, creating a continuous supply of beneficial bacteria that migrate from the intestinal tract to the vagina—a phenomenon that helps maintain long-term vaginal health even after supplementation is reduced.
L. gasseri (Lactobacillus gasseri)
L. gasseri is recognized as one of the four most common Lactobacillus species in healthy vaginal microbiota. Its presence is considered a marker of vaginal health. L. gasseri produces moderate to high levels of lactic acid, maintains optimal pH, and has demonstrated particular effectiveness against Candida albicans overgrowth. For women who suffer from recurrent yeast infections alongside dryness, L. gasseri's dual action—pH balance and antifungal activity—makes it an essential component.
The Ecosystem Stabilizers: Ensuring Long-Term Resilience.
B. animalis (Bifidobacterium animalis)
B. animalis supports overall microbial diversity and ecosystem stability. A healthy vaginal microbiome isn't a monoculture—it's a diverse community where multiple beneficial species coexist and support one another. B. animalis helps create this biodiversity, making the ecosystem more resistant to disruption from antibiotics, stress, dietary changes, or hormonal fluctuations.
L. paracasei (Lactobacillus paracasei)
L. paracasei contributes to metabolic versatility within the microbiome. It can utilize various nutrient sources, producing lactic acid even when glycogen availability fluctuates—a common occurrence during the menopausal transition. This metabolic flexibility helps maintain stable pH even during hormonal fluctuations, preventing the pH "swings" that can trigger infections or discomfort.
B. breve (Bifidobacterium breve)
B. breve supports immune tolerance and anti-inflammatory responses in the vaginal mucosa. By helping the immune system distinguish between beneficial organisms and pathogens, B. breve prevents the unnecessary inflammatory responses that can damage delicate vaginal tissue and disrupt the microbiome.
L. salivarius (Lactobacillus salivarius)
L. salivarius is found in healthy vaginal microbiota and contributes to ecosystem resilience through multiple mechanisms including lactic acid production and antimicrobial compound secretion. Its presence helps create a robust, multi-layered defense system that can withstand challenges without collapsing into dysbiosis.
The Synergistic Effect: Why 13 Strains Work Better Than One.
The power of the Rewind™ probiotic system lies not in any single strain, but in their orchestrated interaction. Here's how they work together to restore natural moisture:
Phase 1 (Days 1-7): Initial Colonization
The Colonizers (L. acidophilus, L. rhamnosus, L. plantarum) begin adhering to vaginal epithelial cells, establishing the first protective layer and initiating lactic acid production.
Phase 2 (Days 7-14): pH Shift and Pathogen Clearance
As Lactobacillus abundance increases, the pH Restoration Team (L. fermentum, L. reuteri, L. gasseri) drives pH from alkaline toward acidic. This pH shift creates an environment where pathogens can no longer thrive, beginning the clearance of infections and odor-causing bacteria.
Phase 3 (Weeks 2-4): Inflammation Reduction and Tissue Healing
The Immune Modulators (B. bifidum, B. longum) reduce inflammation in damaged tissue. As inflammation decreases, epithelial cells regain normal function—including glycogen production. The accumulation of glycogen in suprabasal vaginal epithelial cells is directly stimulated by proper pH and the presence of Lactobacilli.
Phase 4 (Weeks 4-8): Moisture Return and Ecosystem Stabilization
With healthy epithelial cells producing glycogen, Lactobacilli metabolizing it to maintain optimal pH, and inflammation resolved, the vaginal mucosa resumes continuous production of cervicovaginal fluid—the body's natural lubrication. The Ecosystem Stabilizers (B. animalis, L. paracasei, B. breve, L. salivarius) ensure this restored balance remains stable and resilient.
Phase 5 (Month 3+): Self-Sustaining Health
The ecosystem becomes self-maintaining. Epithelial cells shed naturally, releasing glycogen. Lactobacilli metabolize glycogen, producing lactic acid. Lactic acid maintains pH and stimulates continued epithelial health. This creates a positive feedback loop where Lactobacilli and epithelial cells support each other in a self-reinforcing cycle of health.
This is not moisture from a tube that needs daily reapplication. This is your body remembering how to create its own moisture—naturally, continuously, and comfortably—the way it did before menopause.
A 2018 study published in BMC Infectious Diseases demonstrated that long-term vaginal administration of L. rhamnosus resulted in 79.4% resolution of HPV-related cytological abnormalities and 31.2% complete HPV clearance, compared to 37.5% and 11.6% respectively in short-term treatment groups.³ This suggests that sustained probiotic support not only addresses immediate symptoms but also promotes long-term tissue health.
Clinical Outcomes of Probiotic Restoration.
Multiple clinical trials have documented the benefits of targeted probiotic supplementation for vaginal health:
Reduction in Infections: A 2001 study in FEMS Immunology and Medical Microbiology found that daily oral administration of L. rhamnosus GR-1 and L. fermentum RC-14 at doses of 10⁸ viable organisms successfully restored and maintained healthy urogenital flora in women, with 64% conversion of bacterial vaginosis to normal flora.⁴
Maintenance of Vaginal Health: Research published in Scientific Reports (2021) showed that oral or vaginal administration of L. rhamnosus strains produced significant pathogen reduction after 10 days and maintained eubiosis (healthy microbial balance) for up to 30 days after treatment cessation.⁵
Prevention of Recurrence: Women using vaginal-specific probiotics show dramatically lower recurrence rates of bacterial vaginosis and yeast infections compared to antibiotic-only treatment, which often destroys both pathogenic and protective bacteria.
Why 20 Billion CFU and 13 Strains?
The dosage and strain diversity in Rewind™ are based on clinical efficacy data. Research demonstrates that:
- Minimum effective dose for vaginal colonization is 10⁸ (100 million) CFU per strain
- Multi-strain formulations show superior outcomes compared to single-strain products
- Higher CFU counts improve reliability of colonization, especially in women with severely disrupted microbiomes
The 20 billion CFU formulation ensures sufficient viable organisms survive gastric acid and reach both the intestinal and vaginal tracts, where they can exert their protective effects.
Pillar 2: The Renewal System.
Feminine Renewal Complex (802mg Adaptogenic & Circulatory Support).
The Hormonal-Metabolic Disruption of Menopause.
While Pillar 1 addresses the structural foundation of vaginal health, Pillar 2 targets the systemic hormonal and metabolic changes that affect energy, mood, circulation, and sexual desire. The menopausal transition disrupts multiple interconnected systems:
The Stress-Hormone Axis: As estrogen declines, cortisol (the primary stress hormone) often becomes dysregulated. Elevated cortisol suppresses reproductive hormones, impairs immune function, disrupts sleep, and directly inhibits sexual desire. Chronic cortisol elevation creates a state of "survival mode" where the body prioritizes threat response over regeneration and pleasure.
The Circulatory System: Estrogen plays a critical role in maintaining vascular health and blood flow. Post-menopausal women experience decreased nitric oxide production, reduced vascular elasticity, and diminished blood flow to genital tissues. This manifests as decreased arousal, reduced sensitivity, and difficulty achieving orgasm.
The Energy-Mood Connection: Mitochondrial function, cellular energy production, and neurotransmitter synthesis all require adequate micronutrient support. The menopausal transition often reveals nutritional deficiencies that contribute to fatigue, brain fog, and mood dysregulation.
Adaptogenic Support: Stress Reduction and Hormonal Balance.
Ashwagandha Extract (KSM-66®).
Ashwagandha (Withania somnifera) is perhaps the most extensively studied adaptogenic herb for women's health, with particular relevance to menopausal symptoms and sexual function. The KSM-66® extract used in premium formulations represents the highest-concentration, full-spectrum root extract available, backed by numerous gold-standard clinical trials.
Mechanisms of Action:
- Reduces cortisol through modulation of the hypothalamic-pituitary-adrenal (HPA) axis
- Acts on GABA receptors to reduce anxiety and promote calm
- May influence sex hormone production through effects on luteinizing hormone and follicle-stimulating hormone
- Demonstrates anti-inflammatory and antioxidant properties
Clinical Evidence for Women's Sexual Health: A 2015 pilot study published in BioMed Research International examined 50 women with sexual dysfunction randomized to receive 300mg KSM-66® twice daily or placebo for 8 weeks. The ashwagandha group showed remarkable improvements:
- 62.4% increase in arousal domain scores
- 59.4% increase in lubrication
- 82.4% increase in orgasm quality
- 60.9% reduction in sexual distress scores⁶
A subsequent 2022 study in Cureus with 80 women confirmed these findings, demonstrating:
- 59.2% improvement in total Female Sexual Function Index scores
- 52.8% reduction in sexual distress
- 18.3% increase in total sexual encounters
- 31.8% increase in successful sexual encounters
- Significant improvements in overall quality of life measures⁷
Clinical Evidence for Menopausal Symptoms: Research on KSM-66® for menopausal symptoms shows equally impressive results. A randomized controlled trial found that 600mg daily supplementation produced:
- 23.5% reduction in total Menopause Rating Scale scores
- 30.8% decrease in hot flash severity
- 4.02% improvement in menopause-specific quality of life
- Statistically significant increase in serum estradiol
- Decrease in follicle-stimulating hormone⁸
Panax Ginseng & Asian Ginseng.
Ginseng species have been used for centuries in traditional medicine for vitality and sexual health. Modern research confirms these traditional applications, demonstrating that ginseng:
- Supports adrenal function and stress resilience
- Enhances physical and mental energy
- Improves endurance and stamina
- May support healthy testosterone levels (important for libido in women)
Circulatory Enhancement: Blood Flow and Arousal.
L-Arginine (100mg).
L-arginine is a semi-essential amino acid that serves as the precursor to nitric oxide (NO), a critical signaling molecule for vascular health and sexual function. In the body, L-arginine is converted to NO via nitric oxide synthase enzymes, causing vasodilation and increased blood flow.
Relevance to Female Sexual Function: The female sexual arousal response depends heavily on adequate blood flow to the clitoris, labia, and vaginal walls. This vasocongestion causes tissue engorgement, increased sensitivity, and vaginal lubrication through stimulation of the Bartholin's glands. As estrogen declines in menopause, nitric oxide production decreases, vascular elasticity diminishes, and arousal becomes more difficult.
Clinical Evidence: A 2021 systematic review in Current Therapeutic Research evaluated L-arginine (alone or in combination) for hypoactive sexual desire disorder in women. The review found that six of seven studies reported significant increases in Female Sexual Function Index scores or multiple domain improvements. Notably, one study assessed vaginal pulse amplitude and found statistically significant increases in blood flow with L-arginine treatment.⁹
A case study published in the Journal of Sexual Medicine (2023) used ultrasound imaging to quantitatively measure clitoral blood flow before and after application of a gel containing L-arginine and L-citrulline. Results showed increased clitoral blood flow and elevated peak systolic velocity at both 5 and 15 minutes post-application, confirming the compound's ability to enhance genital vasocongestion.¹⁰
A study of combination supplementation (L-arginine with ginkgo, ginseng, damiana, and multivitamins) found that 64% of women reported improvement in sexual desire, with additional improvements in clitoral sensation, reduction of vaginal dryness, and overall satisfaction.¹¹
Ginkgo Biloba.
Ginkgo biloba has demonstrated effects on circulation, particularly cerebral blood flow, and may enhance blood flow to peripheral tissues including genital organs. Its mechanisms include:
- Increased nitric oxide bioavailability
- Improved microcirculation
- Antioxidant protection of vascular endothelium
Ginger Root.
Beyond its well-known digestive benefits, ginger promotes:
- Peripheral circulation and warmth
- Anti-inflammatory effects
- Potential support for arousal through increased blood flow
Traditional Aphrodisiacs: Libido and Desire Support.
Maca Root (Lepidium meyenii).
Maca, a cruciferous root vegetable from the Peruvian Andes, has been used traditionally for centuries to enhance fertility, energy, and sexual function. Modern research supports these traditional uses, particularly for menopausal women.
Clinical Evidence: A systematic review published in Maturitas (2011) evaluated four randomized controlled trials of maca for menopausal symptoms. All trials demonstrated favorable effects using the Kupperman Menopausal Index and Greene Climacteric Score, with improvements in hot flashes, night sweats, mood, and sexual function.¹²
A 2015 double-blind, placebo-controlled trial published in Evidence-Based Complementary and Alternative Medicine examined maca root (1,500mg twice daily) for antidepressant-induced sexual dysfunction in women. The maca group showed higher remission rates of sexual dysfunction, with particularly strong effects in postmenopausal women. Notably, improvements correlated with advancing age but not with estrogen levels, suggesting maca may work through non-estrogenic mechanisms, possibly including androgenic effects.¹³
A 2008 study in Menopause found that maca reduced psychological symptoms including depression and anxiety in postmenopausal women, while improving measures of sexual function independent of estrogen or androgen content.¹⁴
Proposed Mechanisms:
- May act on the hypothalamic-pituitary axis to promote hormonal balance
- Possible androgenic effects at testosterone receptors without affecting serum testosterone
- Rich in bioactive compounds including macamides and macaenes
- Adaptogenic properties that support stress resilience
Tribulus Extract.
Tribulus terrestris has traditional use for enhancing libido and sexual function. Research suggests it may:
- Support healthy testosterone levels through effects on luteinizing hormone
- Enhance sexual desire and satisfaction
- Improve mood and energy
Muira Puama ("Potency Wood").
A traditional Brazilian aphrodisiac, muira puama has been studied for its effects on:
- Female sexual arousal
- Orgasmic response and intensity
- General vitality and libido
Damiana Powder (Turnera diffusa).
Long used in traditional medicine as a female aphrodisiac, damiana may:
- Enhance sensitivity and arousal
- Support mood and reduce anxiety
- Improve sexual satisfaction
Catuaba Powder.
Another traditional Brazilian botanical, catuaba is believed to:
- Enhance energy and stamina
- Support sexual vitality
- Promote overall well-being
Dong Quai ("Female Ginseng").
Used in Traditional Chinese Medicine for women's health, dong quai may:
- Support hormonal harmony
- Reduce menstrual and menopausal discomfort
- Promote reproductive health
Essential Nutrients for Energy and Hormonal Support.
B-Vitamin Complex.
Vitamin B12 (54mcg - 2,250% DV): Critical for cellular energy production, red blood cell formation, and neurological function. B12 deficiency is common in aging populations and contributes to fatigue, brain fog, and mood disturbances.
Vitamin B6 (3.8mg - 224% DV): Essential for hormone metabolism, neurotransmitter synthesis (serotonin, dopamine), and immune function. B6 supports the body's ability to process and balance sex hormones.
Thiamin (1.25mg - 104% DV): Vitamin B1 is required for energy metabolism, converting carbohydrates into usable cellular energy (ATP).
Zinc (26mg - 236% DV).
Zinc plays crucial roles in:
- Immune system function
- Reproductive health and hormone production
- Cellular repair and protein synthesis
- Antioxidant defense
Zinc deficiency is associated with decreased libido, impaired immune function, and hormonal imbalances.
BioPerine® Black Pepper Extract (1mg).
BioPerine® is a standardized extract of piperine from black pepper, included to enhance the bioavailability and absorption of other nutrients and botanicals. Studies show BioPerine® can increase absorption of nutrients by up to 2,000%, ensuring the active ingredients in the formula reach therapeutic levels in the bloodstream.
The Synergistic Two-Pillar Approach.
Why Both Pillars Are Essential.
The innovation of Rewind™ lies not in any single ingredient, but in the recognition that feminine wellness during and after menopause requires simultaneous support of two interconnected systems:
Foundation Without Vitality: A woman may achieve comfortable, infection-free vaginal health through microbiome restoration—but if cortisol remains elevated, circulation remains poor, and energy remains depleted, desire will not return. Comfort alone does not create the physiological state necessary for arousal and pleasure.
Vitality Without Foundation: Conversely, a woman may have balanced hormones and improved energy—but if vaginal dryness, pH imbalance, and recurrent infections persist, intimacy will remain painful and distressing. Desire cannot flourish in a body that associates touch with discomfort.
The Cascading Benefits of Dual Support: When both pillars are addressed simultaneously, they create a positive feedback loop:
- Probiotic restoration → Healthy pH and natural moisture → Comfortable intimacy
- Adaptogenic support → Reduced cortisol → Improved circulation
- Increased blood flow → Enhanced arousal and sensitivity
- Comfortable + aroused → Natural desire returns
- Reduced stress + regular intimacy → Further hormonal balance
- Continued probiotic support → Sustained vaginal health
This is not merely symptom management—it is physiological restoration.
Safety and Tolerability
Clinical Safety Profile.
The ingredients in Rewind™ have extensive safety data from both traditional use and modern clinical trials:
Probiotic Safety: Lactobacillus and Bifidobacterium species are Generally Recognized as Safe (GRAS) by regulatory authorities. Across multiple clinical trials totaling thousands of participants, probiotic supplementation has shown no serious adverse effects. Mild, temporary digestive adjustments (slight bloating or gas) may occur in the first few days as the gut microbiome responds, but these typically resolve quickly.
Ashwagandha Safety: KSM-66® ashwagandha has been used safely in clinical trials at doses up to 600mg daily for extended periods. The extract is well-tolerated with minimal side effects. Rare reports include mild gastrointestinal upset or headache.
L-Arginine Safety: L-arginine is a naturally occurring amino acid with excellent safety profiles in clinical studies. Side effects are uncommon and typically mild (digestive discomfort at very high doses).
Botanical Safety: The traditional aphrodisiac botanicals included in the formula have centuries of safe use in traditional medicine systems and have been studied in modern clinical trials without significant adverse events.
Contraindications and Considerations.
While Rewind™ uses safe, well-studied ingredients, certain populations should exercise caution:
- Pregnancy and Lactation: Not recommended during pregnancy or breastfeeding due to limited safety data for some ingredients
- Immunosuppression: Individuals taking immunosuppressant medications should consult healthcare providers before using probiotic supplements
- Hormone-Sensitive Conditions: Though Rewind™ is hormone-free, women with hormone-sensitive conditions should discuss use with their healthcare provider
- Medication Interactions: Women taking medications, particularly antidepressants, blood pressure medications, or diabetes medications, should consult healthcare providers to assess potential interactions
As with any dietary supplement, it is advisable to consult with a qualified healthcare provider before beginning use, particularly for those with underlying medical conditions or taking prescription medications.
Dosing and Administration.
The Rewind™ system is divided into two bottles to optimize the timing and absorption of each complex:
Bottle 1: Flora Restoration Complex
- Take 1 capsule daily in the morning
- Best taken on an empty stomach or with light food
- Consistent daily timing supports probiotic colonization
Bottle 2: Feminine Renewal Complex
- Take 2 capsules daily with a meal
- Evening administration may be preferable for adaptogenic herbs
- Fat-soluble nutrients benefit from dietary fat for absorption
This separation ensures:
- Probiotics are delivered at optimal timing for survival and colonization
- Adaptogens and nutrients are absorbed with food for maximum bioavailability
- Each ingredient reaches full clinical dosages
Expected Timeline for Results.
Based on clinical research and customer feedback data:
Weeks 1-2:
- Initial improvements in vaginal comfort
- Reduced irritation and dryness
- Beginning of probiotic colonization
Weeks 3-4:
- Natural moisture returning
- Reduction in discharge and odor
- Improved pH balance
- Enhanced energy levels
Months 2-3:
- Significantly reduced or eliminated recurrent infections
- Comfortable, pain-free intimacy
- Improved mood stability
- Enhanced circulation and sensitivity
- Natural desire beginning to return
Month 6 and beyond:
- Sustained vaginal health and microbiome balance
- Consistent energy and vitality
- Normalized stress response
- Restored intimate wellness
Individual responses vary based on baseline health status, severity of symptoms, and consistency of use.
Conclusion: A New Paradigm for Menopausal Wellness.
Rewind™ represents a departure from the conventional approach to menopausal health, which typically treats symptoms in isolation without addressing root physiological causes. By simultaneously supporting vaginal microbiome health and systemic hormonal-metabolic balance, Rewind™ offers women a comprehensive, science-based approach to reclaiming their feminine vitality.
The formulation draws on decades of clinical research demonstrating the efficacy of targeted probiotic strains for vaginal health, adaptogenic herbs for stress and hormonal balance, and circulatory-supporting nutrients for sexual function. Rather than masking symptoms or introducing synthetic hormones, Rewind™ provides the body with the specific nutritional support it needs to restore its own natural balance.
For the millions of women navigating the challenges of perimenopause and menopause, Rewind™ offers not just symptom relief, but the possibility of thriving—feeling comfortable, energized, and alive in their own bodies once again.
References.
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- Bertuccini L, Russo R, Iosi F, Superti F. Effects of Lactobacillus rhamnosus and Lactobacillus acidophilus on bacterial vaginal pathogens. Front Cell Infect Microbiol. 2021. doi:10.3389/fcimb.2023.1128958
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- Lee MS, Shin BC, Yang EJ, et al. Maca (Lepidium meyenii) for treatment of menopausal symptoms: a systematic review. Maturitas. 2011;70(3):227-233. doi:10.1016/j.maturitas.2011.07.017
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Disclaimer.
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Rewind™ is a comprehensive feminine wellness system designed to support women through perimenopause, menopause, and beyond. Formulated with clinically-studied ingredients, Rewind™ represents the intersection of traditional botanical wisdom and modern nutritional science.
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